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PLOS BiologyThe liver <a href="https://fediscience.org/tags/transcriptome" class="mention hashtag" rel="nofollow noopener" target="_blank">#transcriptome</a> is highly sensitive to metabolic cues. By characterizing nuclear protein <a href="https://fediscience.org/tags/OGlcNAcylation" class="mention hashtag" rel="nofollow noopener" target="_blank">#OGlcNAcylation</a> in mouse <a href="https://fediscience.org/tags/liver" class="mention hashtag" rel="nofollow noopener" target="_blank">#liver</a> during the day, this study shows how shifts in a nutrient-sensitive <a href="https://fediscience.org/tags/PTM" class="mention hashtag" rel="nofollow noopener" target="_blank">#PTM</a> may shape transcriptional regulation <a href="https://fediscience.org/@PLOSBiology" class="u-url mention" rel="nofollow noopener" target="_blank">@PLOSBiology</a> <a href="https://plos.io/3KuS7m1" rel="nofollow noopener" translate="no" target="_blank">https://plos.io/3KuS7m1</a>

nf-corePipeline release! nf-core/denovotranscript v1.2.1 - nf-core/denovotranscript v1.2.1!Please see the changelog: <a href="https://github.com/nf-core/denovotranscript/releases/tag/1.2.1" rel="nofollow noopener" translate="no" target="_blank">https://github.com/nf-core/denovotranscript/releases/tag/1.2.1</a><a href="https://mstdn.science/tags/denovoassembly" class="mention hashtag" rel="nofollow noopener" target="_blank">#denovoassembly</a> <a href="https://mstdn.science/tags/rnaseq" class="mention hashtag" rel="nofollow noopener" target="_blank">#rnaseq</a> <a href="https://mstdn.science/tags/transcriptome" class="mention hashtag" rel="nofollow noopener" target="_blank">#transcriptome</a> <a href="https://mstdn.science/tags/nfcore" class="mention hashtag" rel="nofollow noopener" target="_blank">#nfcore</a> <a href="https://mstdn.science/tags/openscience" class="mention hashtag" rel="nofollow noopener" target="_blank">#openscience</a> <a href="https://mstdn.science/tags/nextflow" class="mention hashtag" rel="nofollow noopener" target="_blank">#nextflow</a> <a href="https://mstdn.science/tags/bioinformatics" class="mention hashtag" rel="nofollow noopener" target="_blank">#bioinformatics</a>

nf-corePipeline release! nf-core/denovotranscript v1.2.0 - nf-core/denovotranscript v1.2.0!Please see the changelog: <a href="https://github.com/nf-core/denovotranscript/releases/tag/1.2.0" rel="nofollow noopener" translate="no" target="_blank">https://github.com/nf-core/denovotranscript/releases/tag/1.2.0</a><a href="https://mstdn.science/tags/denovoassembly" class="mention hashtag" rel="nofollow noopener" target="_blank">#denovoassembly</a> <a href="https://mstdn.science/tags/rnaseq" class="mention hashtag" rel="nofollow noopener" target="_blank">#rnaseq</a> <a href="https://mstdn.science/tags/transcriptome" class="mention hashtag" rel="nofollow noopener" target="_blank">#transcriptome</a> <a href="https://mstdn.science/tags/nfcore" class="mention hashtag" rel="nofollow noopener" target="_blank">#nfcore</a> <a href="https://mstdn.science/tags/openscience" class="mention hashtag" rel="nofollow noopener" target="_blank">#openscience</a> <a href="https://mstdn.science/tags/nextflow" class="mention hashtag" rel="nofollow noopener" target="_blank">#nextflow</a> <a href="https://mstdn.science/tags/bioinformatics" class="mention hashtag" rel="nofollow noopener" target="_blank">#bioinformatics</a>

CellBioNewsDo or die: How <a href="https://scientificnetwork.de/tags/soybeans" class="mention hashtag" rel="nofollow noopener" target="_blank">#soybeans</a> tackle <a href="https://scientificnetwork.de/tags/nematode" class="mention hashtag" rel="nofollow noopener" target="_blank">#nematode</a> invaders.<a href="https://scientificnetwork.de/tags/agriculture" class="mention hashtag" rel="nofollow noopener" target="_blank">#agriculture</a> <a href="https://scientificnetwork.de/tags/transcriptome" class="mention hashtag" rel="nofollow noopener" target="_blank">#transcriptome</a> <a href="https://scientificnetwork.de/tags/RNA" class="mention hashtag" rel="nofollow noopener" target="_blank">#RNA</a> <a href="https://phys.org/news/2025-01-die-soybeans-tackle-nematode-invaders.html" rel="nofollow noopener" translate="no" target="_blank">https://phys.org/news/2025-01-die-soybeans-tackle-nematode-invaders.html</a>

Victoria Stuart 🇨🇦 🏳️‍⚧️Human molecular map contributes to understanding of disease mechanisms <a href="https://www.sciencedaily.com/releases/2024/09/240911175947.htm" rel="nofollow noopener" translate="no" target="_blank">https://www.sciencedaily.com/releases/2024/09/240911175947.htm</a>Roadmap to molecular human linking multiomics w. population traits, diabetes subtype <a href="https://www.nature.com/articles/s41467-024-51134-x" rel="nofollow noopener" translate="no" target="_blank">https://www.nature.com/articles/s41467-024-51134-x</a>6,304 quantitative molec. traits 1,221,345 genetic variants methylation @ 470,837 DNA CpG sites gene expression: 57,000 transcripts<a href="https://mastodon.social/tags/metabolome" class="mention hashtag" rel="nofollow noopener" target="_blank">#metabolome</a> <a href="https://mastodon.social/tags/connectome" class="mention hashtag" rel="nofollow noopener" target="_blank">#connectome</a> <a href="https://mastodon.social/tags/interactome" class="mention hashtag" rel="nofollow noopener" target="_blank">#interactome</a> <a href="https://mastodon.social/tags/genotype" class="mention hashtag" rel="nofollow noopener" target="_blank">#genotype</a> <a href="https://mastodon.social/tags/phenotype" class="mention hashtag" rel="nofollow noopener" target="_blank">#phenotype</a> <a href="https://mastodon.social/tags/IndividualVariation" class="mention hashtag" rel="nofollow noopener" target="_blank">#IndividualVariation</a> <a href="https://mastodon.social/tags/transcriptome" class="mention hashtag" rel="nofollow noopener" target="_blank">#transcriptome</a> <a href="https://mastodon.social/tags/multiomics" class="mention hashtag" rel="nofollow noopener" target="_blank">#multiomics</a> <a href="https://mastodon.social/tags/omics" class="mention hashtag" rel="nofollow noopener" target="_blank">#omics</a> <a href="https://mastodon.social/tags/disease" class="mention hashtag" rel="nofollow noopener" target="_blank">#disease</a> <a href="https://mastodon.social/tags/MolecularEpidemiology" class="mention hashtag" rel="nofollow noopener" target="_blank">#MolecularEpidemiology</a> <a href="https://mastodon.social/tags/GeneExpression" class="mention hashtag" rel="nofollow noopener" target="_blank">#GeneExpression</a>

Stephen Matheson🌵🌲Loic Binan of the Broad: All-optical genetic screens of intracellular and intercellular <a href="https://fediscience.org/tags/transcriptional" class="mention hashtag" rel="nofollow noopener" target="_blank">#transcriptional</a> circuits with Perturb-FISHVarious CRISPR-based methods to look (multiplexed) at outcomes after knockdown to explore gene expression circuits, those are great, but want richer data (morphology etc)one guide per cell (knock down one gene per cell) see <a href="https://fediscience.org/tags/transcriptome" class="mention hashtag" rel="nofollow noopener" target="_blank">#transcriptome</a> via MERFISH, then identify the perturbed gene via in situ T7 transcription (same chemistry as MERFISH)<a href="https://fediscience.org/tags/CSSingleCells23" class="mention hashtag" rel="nofollow noopener" target="_blank">#CSSingleCells23</a>1/2

Lukas VFN 🇪🇺<a href="https://scholar.social/tags/Philippines" class="mention hashtag" rel="nofollow noopener" target="_blank">#Philippines</a> research offers hope for conserving enigmatic Rafflesia <a href="https://scholar.social/tags/plants" class="mention hashtag" rel="nofollow noopener" target="_blank">#plants</a> <a href="https://news.mongabay.com/2023/07/philippines-research-offers-hope-for-conserving-enigmatic-rafflesia-plants/" rel="nofollow noopener" target="_blank">https://news.mongabay.com/2023/07/philippines-research-offers-hope-for-conserving-enigmatic-rafflesia-plants/</a>The seed <a href="https://scholar.social/tags/transcriptome" class="mention hashtag" rel="nofollow noopener" target="_blank">#transcriptome</a> of Rafflesia reveals <a href="https://scholar.social/tags/HorizontalGeneTransfer" class="mention hashtag" rel="nofollow noopener" target="_blank">#HorizontalGeneTransfer</a> and convergent <a href="https://scholar.social/tags/evolution" class="mention hashtag" rel="nofollow noopener" target="_blank">#evolution</a>: Implications for conserving the world's largest flower: Jeanmaire Molina et al. <a href="https://nph.onlinelibrary.wiley.com/doi/10.1002/ppp3.10370" rel="nofollow noopener" target="_blank">https://nph.onlinelibrary.wiley.com/doi/10.1002/ppp3.10370</a>"They found no genes pointing to a symbiotic relationship between <a href="https://scholar.social/tags/Rafflesia" class="mention hashtag" rel="nofollow noopener" target="_blank">#Rafflesia</a> and <a href="https://scholar.social/tags/fungi" class="mention hashtag" rel="nofollow noopener" target="_blank">#fungi</a>, suggesting that unlike <a href="https://scholar.social/tags/orchids" class="mention hashtag" rel="nofollow noopener" target="_blank">#orchids</a>, Rafflesia may not need nutrients from fungi for successful germination."

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