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PLOS BiologyThe calcium surge that starts <a href="https://fediscience.org/tags/embryogenesis" class="mention hashtag" rel="nofollow noopener" target="_blank">#embryogenesis</a> varies across species. This Primer explores a <a href="https://fediscience.org/@PLOSBiology" class="u-url mention" rel="nofollow noopener" target="_blank">@PLOSBiology</a> study of <a href="https://fediscience.org/tags/zebrafish" class="mention hashtag" rel="nofollow noopener" target="_blank">#zebrafish</a>, revealing that protease-activated receptors mediate a calcium signal that initiates <a href="https://fediscience.org/tags/egg" class="mention hashtag" rel="nofollow noopener" target="_blank">#egg</a> activation before <a href="https://fediscience.org/tags/sperm" class="mention hashtag" rel="nofollow noopener" target="_blank">#sperm</a> entry. Paper: <a href="https://plos.io/467nrzY" rel="nofollow noopener" translate="no" target="_blank">https://plos.io/467nrzY</a> Primer: <a href="https://plos.io/3TuRvy1" rel="nofollow noopener" translate="no" target="_blank">https://plos.io/3TuRvy1</a>

PLOS BiologyAnimal development requires <a href="https://fediscience.org/tags/egg" class="mention hashtag" rel="nofollow noopener" target="_blank">#egg</a> activation, which is initiated by calcium waves, but how does this happen? This study shows that protease activation of the Par2a receptor on the <a href="https://fediscience.org/tags/zebrafish" class="mention hashtag" rel="nofollow noopener" target="_blank">#zebrafish</a> egg surface is required for successful <a href="https://fediscience.org/tags/fertilization" class="mention hashtag" rel="nofollow noopener" target="_blank">#fertilization</a> <a href="https://fediscience.org/@PLOSBiology" class="u-url mention" rel="nofollow noopener" target="_blank">@PLOSBiology</a> <a href="https://plos.io/467nrzY" rel="nofollow noopener" translate="no" target="_blank">https://plos.io/467nrzY</a>

preLightsA topographic code for behavioural flexibility? Muhammed Sinan Malik wrote a preLight on work from Emre Yaksi & team mapping dorsal raphe dynamics to sensory-motor decisions in zebrafish. 🐟 <a href="https://biologists.social/tags/preprint" class="mention hashtag" rel="nofollow noopener" target="_blank">#preprint</a> Check it out! ⬇️ 👀 <a href="https://prelights.biologists.com/highlights/topographically-organized-dorsal-raphe-activity-modulates-forebrain-sensory-motor-computations-and-adaptive-behaviors/" rel="nofollow noopener" translate="no" target="_blank">https://prelights.biologists.com/highlights/topographically-organized-dorsal-raphe-activity-modulates-forebrain-sensory-motor-computations-and-adaptive-behaviors/</a><a href="https://biologists.social/tags/biology" class="mention hashtag" rel="nofollow noopener" target="_blank">#biology</a> <a href="https://biologists.social/tags/neuroscience" class="mention hashtag" rel="nofollow noopener" target="_blank">#neuroscience</a> <a href="https://biologists.social/tags/zebrafish" class="mention hashtag" rel="nofollow noopener" target="_blank">#zebrafish</a> <a href="https://biologists.social/tags/cognition" class="mention hashtag" rel="nofollow noopener" target="_blank">#cognition</a> <a href="https://biologists.social/tags/behaviour" class="mention hashtag" rel="nofollow noopener" target="_blank">#behaviour</a>

preLights<a href="https://biologists.social/tags/spotLights" class="mention hashtag" rel="nofollow noopener" target="_blank">#spotLights</a> hits episode 10! 🙌Jonathan Townson talks to Helena Crellin (<a href="https://biologists.social/tags/BuckleyLab" class="mention hashtag" rel="nofollow noopener" target="_blank">#BuckleyLab</a>) about her <a href="https://biologists.social/tags/preprint" class="mention hashtag" rel="nofollow noopener" target="_blank">#preprint</a> introducing an optogenetic approach to study "how forces are propagated through complex tissues during development" in <a href="https://biologists.social/tags/zebrafish" class="mention hashtag" rel="nofollow noopener" target="_blank">#zebrafish</a> 🧠🐟Listen below! 🎧 🎙️ <a href="https://youtu.be/6uce4whDt2M" rel="nofollow noopener" translate="no" target="_blank">https://youtu.be/6uce4whDt2M</a><a href="https://biologists.social/tags/biologists100" class="mention hashtag" rel="nofollow noopener" target="_blank">#biologists100</a> <a href="https://biologists.social/tags/optogenetics" class="mention hashtag" rel="nofollow noopener" target="_blank">#optogenetics</a> <a href="https://biologists.social/tags/OpenScience" class="mention hashtag" rel="nofollow noopener" target="_blank">#OpenScience</a> <a href="https://biologists.social/tags/podcast" class="mention hashtag" rel="nofollow noopener" target="_blank">#podcast</a>

PLOS Biology<a href="https://fediscience.org/tags/SensoryGating" class="mention hashtag" rel="nofollow noopener" target="_blank">#SensoryGating</a> helps animals to distinguish threatening & non-threatening stimuli. This study reveals a mechanism whereby <a href="https://fediscience.org/tags/cadherin" class="mention hashtag" rel="nofollow noopener" target="_blank">#cadherin</a> 16 (cdh16)-dependent changes in the corpuscle of Stannius regulate whole-body <a href="https://fediscience.org/tags/calcium" class="mention hashtag" rel="nofollow noopener" target="_blank">#calcium</a> homeostasis & sensory gating in <a href="https://fediscience.org/tags/zebrafish" class="mention hashtag" rel="nofollow noopener" target="_blank">#zebrafish</a> <a href="https://fediscience.org/@PLOSBiology" class="u-url mention" rel="nofollow noopener" target="_blank">@PLOSBiology</a> <a href="https://plos.io/4m8XZA2" rel="nofollow noopener" translate="no" target="_blank">https://plos.io/4m8XZA2</a>

PLOS BiologyAre action potentials in vertebrate muscle essential for contraction? This study of <a href="https://fediscience.org/tags/zebrafish" class="mention hashtag" rel="nofollow noopener" target="_blank">#zebrafish</a> lacking <a href="https://fediscience.org/tags/SodiumChannel" class="mention hashtag" rel="nofollow noopener" target="_blank">#SodiumChannel</a> NaV1.4 reveals that NaVs are dispensable for <a href="https://fediscience.org/tags/muscle" class="mention hashtag" rel="nofollow noopener" target="_blank">#muscle</a> contraction, so the need for muscle <a href="https://fediscience.org/tags/ActionPotentials" class="mention hashtag" rel="nofollow noopener" target="_blank">#ActionPotentials</a> can vary between vertebrates <a href="https://fediscience.org/@PLOSBiology" class="u-url mention" rel="nofollow noopener" target="_blank">@PLOSBiology</a> <a href="https://plos.io/42EXQwx" rel="nofollow noopener" translate="no" target="_blank">https://plos.io/42EXQwx</a>

Albert Cardona"Forecasting Whole-Brain Neuronal Activity from Volumetric Video", Immer et al. 2025 (with Florian Engert, Jeff Lichtman, Misha Ahrens, Viren Jain and Michal Januszewski) <a href="https://www.arxiv.org/abs/2503.00073" rel="nofollow noopener" translate="no" target="_blank">https://www.arxiv.org/abs/2503.00073</a>"ZAPBench: a benchmark for whole-brain activity prediction in zebrafish", Lueckmann et al. 2025 <a href="https://openreview.net/pdf?id=oCHsDpyawq" rel="nofollow noopener" translate="no" target="_blank">https://openreview.net/pdf?id=oCHsDpyawq</a><a href="https://mathstodon.xyz/tags/ZAPBench" class="mention hashtag" rel="nofollow noopener" target="_blank">#ZAPBench</a> <a href="https://mathstodon.xyz/tags/neuroscience" class="mention hashtag" rel="nofollow noopener" target="_blank">#neuroscience</a> <a href="https://mathstodon.xyz/tags/zebrafish" class="mention hashtag" rel="nofollow noopener" target="_blank">#zebrafish</a> <a href="https://mathstodon.xyz/tags/CalciumImaging" class="mention hashtag" rel="nofollow noopener" target="_blank">#CalciumImaging</a> <a href="https://mathstodon.xyz/tags/CompNeurosci" class="mention hashtag" rel="nofollow noopener" target="_blank">#CompNeurosci</a>

preLightsNeural blueprint for credit assignment in zebrafish. 🐟Muhammed Sinan Malik highlights work describing how motor actions are linked with sensory feedback via the dorsal habenula–interpeduncular pathway. <a href="https://biologists.social/tags/preprint" class="mention hashtag" rel="nofollow noopener" target="_blank">#preprint</a> from Emanuele Paoli & team <a href="https://biologists.social/tags/PortuguesLab" class="mention hashtag" rel="nofollow noopener" target="_blank">#PortuguesLab</a> <a href="https://biologists.social/tags/TU_Muenchen" class="mention hashtag" rel="nofollow noopener" target="_blank">#TU_Muenchen</a>preLight ⬇️ 👀 <a href="https://prelights.biologists.com/highlights/a-zebrafish-circuit-for-behavioral-credit-assignment-2/" rel="nofollow noopener" translate="no" target="_blank">https://prelights.biologists.com/highlights/a-zebrafish-circuit-for-behavioral-credit-assignment-2/</a><a href="https://biologists.social/tags/biology" class="mention hashtag" rel="nofollow noopener" target="_blank">#biology</a> <a href="https://biologists.social/tags/neuroscience" class="mention hashtag" rel="nofollow noopener" target="_blank">#neuroscience</a> <a href="https://biologists.social/tags/zebrafish" class="mention hashtag" rel="nofollow noopener" target="_blank">#zebrafish</a> <a href="https://biologists.social/tags/neurobiology" class="mention hashtag" rel="nofollow noopener" target="_blank">#neurobiology</a> <a href="https://biologists.social/tags/behaviour" class="mention hashtag" rel="nofollow noopener" target="_blank">#behaviour</a> <a href="https://biologists.social/tags/cognition" class="mention hashtag" rel="nofollow noopener" target="_blank">#cognition</a>

eLifeBehavioural <a href="https://fediscience.org/tags/pharmacology" class="mention hashtag" rel="nofollow noopener" target="_blank">#pharmacology</a> predicts signalling pathways that could be drug targets in <a href="https://fediscience.org/tags/zebrafish" class="mention hashtag" rel="nofollow noopener" target="_blank">#zebrafish</a> with <a href="https://fediscience.org/tags/Alzheimer" class="mention hashtag" rel="nofollow noopener" target="_blank">#Alzheimer</a>’s disease risk genes. <a href="https://elifesciences.org/articles/96839?utm_source=mastodon&utm_medium=social&utm_campaign=organic" rel="nofollow noopener" translate="no" target="_blank">https://elifesciences.org/articles/96839?utm_source=mastodon&utm_medium=social&utm_campaign=organic</a>

MadScientistExtremely honored to receive this Award from a Society I value, full of colleagues and friends. Dev Bio is well and alive, and we're proof of it! Dev Bio FTW <a href="https://mastodon.social/tags/science" class="mention hashtag" rel="nofollow noopener" target="_blank">#science</a> <a href="https://mastodon.social/tags/zebrafish" class="mention hashtag" rel="nofollow noopener" target="_blank">#zebrafish</a> <a href="https://mastodon.social/tags/DevelopmentalBiology" class="mention hashtag" rel="nofollow noopener" target="_blank">#DevelopmentalBiology</a> <a href="https://mastodon.social/tags/PostdocLife" class="mention hashtag" rel="nofollow noopener" target="_blank">#PostdocLife</a> <a href="https://mastodon.social/tags/PhDChat" class="mention hashtag" rel="nofollow noopener" target="_blank">#PhDChat</a>

Albert CardonaParallels between the <a href="https://mathstodon.xyz/tags/zebrafish" class="mention hashtag" rel="nofollow noopener" target="_blank">#zebrafish</a> head direction neuron circuits and the <a href="https://mathstodon.xyz/tags/Drosophila" class="mention hashtag" rel="nofollow noopener" target="_blank">#Drosophila</a> central complex:"we asked if and how the recently identified HD [head direction] cells in the larval zebrafish ... incorporate visual information.""zebrafish HD cells can reliably track the orientation of multiple visual scenes, exploiting both landmark and optic flow cues. The mapping between landmark cues and the heading estimates is idiosyncratic across fish, and experience-dependent.""The physiological and morphological parallels suggest that a Hebbian mechanism similar to the fly ring neuron is at work in the habenula axons."From: "Mechanisms for plastic landmark anchoring in zebrafish compass neurons" by Tanaka and Portugues, 2024 <a href="https://www.biorxiv.org/content/10.1101/2024.12.13.628331v2" rel="nofollow noopener" translate="no" target="_blank">https://www.biorxiv.org/content/10.1101/2024.12.13.628331v2</a><a href="https://mathstodon.xyz/tags/neuroscience" class="mention hashtag" rel="nofollow noopener" target="_blank">#neuroscience</a> <a href="https://mathstodon.xyz/tags/CentralComplex" class="mention hashtag" rel="nofollow noopener" target="_blank">#CentralComplex</a>

PLOS BiologyThis Primer explores a new <a href="https://fediscience.org/tags/PLOSBiology" class="mention hashtag" rel="nofollow noopener" target="_blank">#PLOSBiology</a> study revealing the role of the mRNA-surveillance mechanism of no-go decay (NGD) in regulating gene expression during embryonic development in <a href="https://fediscience.org/tags/zebrafish" class="mention hashtag" rel="nofollow noopener" target="_blank">#zebrafish</a>. Primer: <a href="https://plos.io/4frsf4B" rel="nofollow noopener" translate="no" target="_blank">https://plos.io/4frsf4B</a> Paper: <a href="https://plos.io/4g4RESq" rel="nofollow noopener" translate="no" target="_blank">https://plos.io/4g4RESq</a>

preLightsZebrafish can sense numbers! 🔢🐟In his first <a href="https://biologists.social/tags/preLight" class="mention hashtag" rel="nofollow noopener" target="_blank">#preLight</a>, Muhammed Sinan Malik highlights work from Peter Luu & colleagues revealing early emergence of number-selective neurons in larval zebrafish. <a href="https://biologists.social/tags/preprint" class="mention hashtag" rel="nofollow noopener" target="_blank">#preprint</a>Take a look! ⬇️ 👀 <a href="https://prelights.biologists.com/highlights/neural-basis-of-number-sense-in-larval-zebrafish/" rel="nofollow noopener" translate="no" target="_blank">https://prelights.biologists.com/highlights/neural-basis-of-number-sense-in-larval-zebrafish/</a><a href="https://biologists.social/tags/biology" class="mention hashtag" rel="nofollow noopener" target="_blank">#biology</a> <a href="https://biologists.social/tags/behavior" class="mention hashtag" rel="nofollow noopener" target="_blank">#behavior</a> <a href="https://biologists.social/tags/cognition" class="mention hashtag" rel="nofollow noopener" target="_blank">#cognition</a> <a href="https://biologists.social/tags/neuroscience" class="mention hashtag" rel="nofollow noopener" target="_blank">#neuroscience</a> <a href="https://biologists.social/tags/zebrafish" class="mention hashtag" rel="nofollow noopener" target="_blank">#zebrafish</a>

idw_onlinecutting-edge research results in <a href="https://idw-online.social/tags/biophysics" class="mention hashtag" rel="nofollow noopener" target="_blank">#biophysics</a>: @CampasLab at @PoLDresden discovered together with colleagues of <a href="https://idw-online.social/tags/UCSB" class="mention hashtag" rel="nofollow noopener" target="_blank">#UCSB</a>, that the <a href="https://idw-online.social/tags/tissue" class="mention hashtag" rel="nofollow noopener" target="_blank">#tissue</a> <a href="https://idw-online.social/tags/stiffness" class="mention hashtag" rel="nofollow noopener" target="_blank">#stiffness</a> in <a href="https://idw-online.social/tags/zebrafish" class="mention hashtag" rel="nofollow noopener" target="_blank">#zebrafish</a> retina depends on the packing of <a href="https://idw-online.social/tags/nuclei" class="mention hashtag" rel="nofollow noopener" target="_blank">#nuclei</a>. <a href="https://nachrichten.idw-online.de/2024/08/12/der-verborgene-architekt-wie-zellkerne-augen-und-gehirn-organisieren" rel="nofollow noopener" translate="no" target="_blank">https://nachrichten.idw-online.de/2024/08/12/der-verborgene-architekt-wie-zellkerne-augen-und-gehirn-organisieren</a>

PLOS BiologyWe have v few models of natural virus infection in <a href="https://fediscience.org/tags/zebrafish" class="mention hashtag" rel="nofollow noopener" target="_blank">#zebrafish</a>. @MostowyLab explores a <a href="https://fediscience.org/tags/PLOSBiology" class="mention hashtag" rel="nofollow noopener" target="_blank">#PLOSBiology</a> study that uses meta-transcriptomics & co-housing experiments to identify natural <a href="https://fediscience.org/tags/virus" class="mention hashtag" rel="nofollow noopener" target="_blank">#virus</a> pathogens of lab zebrafish. Primer: <a href="https://plos.io/3xcy6ue" rel="nofollow noopener" translate="no" target="_blank">https://plos.io/3xcy6ue</a> Paper: <a href="https://plos.io/3yJBRba" rel="nofollow noopener" translate="no" target="_blank">https://plos.io/3yJBRba</a>

Thiago Carvalho'To investigate differences between the HSPCs emerging from the hemogenic endothelium, Torcq et al. studied zebrafish embryos that had been modified so that one of the proteins involved in sensing cell polarity – where the top and bottom of the cell are located – was fluorescent.' <a href="https://qoto.org/tags/Immunology" class="mention hashtag" rel="nofollow noopener" target="_blank">#Immunology</a> <a href="https://qoto.org/tags/Zebrafish" class="mention hashtag" rel="nofollow noopener" target="_blank">#Zebrafish</a> <a href="https://elifesciences.org/digests/91429/emerging-blood-and-immune-cells?utm_source=twitter&utm_medium=social&utm_campaign=organic" rel="nofollow noopener" target="_blank">https://elifesciences.org/digests/91429/emerging-blood-and-immune-cells?utm_source=twitter&utm_medium=social&utm_campaign=organic</a>

PLOS Biology"I caught it in the pet shop." @keirballa @james_gagnon &co show that <a href="https://fediscience.org/tags/zebrafish" class="mention hashtag" rel="nofollow noopener" target="_blank">#zebrafish</a> from the pet trade harbor many microbes that can be transmitted to experimentally tractable lab zebrafish for further study (incl the first zebrafish <a href="https://fediscience.org/tags/birnavirus" class="mention hashtag" rel="nofollow noopener" target="_blank">#birnavirus</a>) <a href="https://fediscience.org/tags/PLOSBiology" class="mention hashtag" rel="nofollow noopener" target="_blank">#PLOSBiology</a> <a href="https://plos.io/3yJBRba" rel="nofollow noopener" translate="no" target="_blank">https://plos.io/3yJBRba</a>

PLOS BiologyPotassium channels regulate the scale of <a href="https://fediscience.org/tags/fish" class="mention hashtag" rel="nofollow noopener" target="_blank">#fish</a> fins, but how? This study shows that the scale of <a href="https://fediscience.org/tags/zebrafish" class="mention hashtag" rel="nofollow noopener" target="_blank">#zebrafish</a> embryonic pectoral fins is determined by the regulation of intracellular K+ by retinoic acid via Rcan2 & <a href="https://fediscience.org/tags/PotassiumChannel" class="mention hashtag" rel="nofollow noopener" target="_blank">#PotassiumChannel</a> Kcnk5b <a href="https://fediscience.org/tags/PLOSBiology" class="mention hashtag" rel="nofollow noopener" target="_blank">#PLOSBiology</a> <a href="https://plos.io/3IOCu53" rel="nofollow noopener" translate="no" target="_blank">https://plos.io/3IOCu53</a>

eLifeA valuable syngeneic <a href="https://fediscience.org/tags/zebrafish" class="mention hashtag" rel="nofollow noopener" target="_blank">#zebrafish</a> model for studying <a href="https://fediscience.org/tags/glioblastoma" class="mention hashtag" rel="nofollow noopener" target="_blank">#glioblastoma</a>. <a href="https://fediscience.org/tags/Cancer" class="mention hashtag" rel="nofollow noopener" target="_blank">#Cancer</a> <a href="https://fediscience.org/tags/CancerBiology" class="mention hashtag" rel="nofollow noopener" target="_blank">#CancerBiology</a> <a href="https://fediscience.org/tags/ReviewedPreprint" class="mention hashtag" rel="nofollow noopener" target="_blank">#ReviewedPreprint</a> <a href="https://elifesciences.org/reviewed-preprints/93077?utm_source=mastodon&utm_medium=social&utm_campaign=organic" rel="nofollow noopener" translate="no" target="_blank">https://elifesciences.org/reviewed-preprints/93077?utm_source=mastodon&utm_medium=social&utm_campaign=organic</a>

PLOS BiologyIn mammals, starburst <a href="https://fediscience.org/tags/AmacrineCells" class="mention hashtag" rel="nofollow noopener" target="_blank">#AmacrineCells</a> are key to motion vision. @TaYoshimatsu & <a href="https://ecoevo.social/@TomBaden" class="u-url mention" rel="nofollow noopener" target="_blank">@TomBaden</a> explore a <a href="https://fediscience.org/tags/PLOSBiology" class="mention hashtag" rel="nofollow noopener" target="_blank">#PLOSBiology</a> study showing that <a href="https://fediscience.org/tags/zebrafish" class="mention hashtag" rel="nofollow noopener" target="_blank">#zebrafish</a> also have amacrine cells, alongside a 2nd pair of starburst-like neurons, but neither appears to be strongly motion selective. Primer: <a href="https://plos.io/3uUZNXy" rel="nofollow noopener" translate="no" target="_blank">https://plos.io/3uUZNXy</a> Paper: <a href="https://plos.io/3I6q3B0" rel="nofollow noopener" translate="no" target="_blank">https://plos.io/3I6q3B0</a>

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